AN UNBIASED VIEW OF PENTOBARBITAL SODIUM ADVERSE EFFECTS

pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of CYP3A4 inducers could lower sufentanil concentrations and efficacy, probably precipitating withdrawal syndrome in clients who have formulated Bodily dependence to sufentanil. Discontinuation